| Guardian | Lane boss | One per lane | Described as the giant structure with the torch on each lane. |
| Walker | Structure boss | Core objective | Listed among Deadlock's core objectives alongside the Guardians, Shrines and Patron. |
| Shrine | Structure boss | Core objective | Part of the same core objective set as the Guardians, Walkers and Patron. |
| Patron | Final base objective | Each team's base | The objective tied to each team's base, overhauled together with the bases in the Old Gods, New Blood update. |
| Mid-Boss (Rejuvenator) | Neutral objective | Contested | The neutral objective named in Deadlock's core objective set. |
| Haunts | Neutral creatures | Throughout the city | New neutrals replacing the old ones, with new behaviours and HUD-shown soul value and comparative difficulty. |